Products

Span

Short Description:


Product Detail

FAQ

Product Tags

I.Overview

Sorbitan fatty acid ester (Span) is a non-ionic surfactant regarding fatty acids groups as the hydrophobic part and sorbitan groups as the hydrophilic part. Polyoxyethylene (20) sorbitan fatty acid ester (Tween) is a non-ionic surfactant regarding fatty acids groups as the hydrophobic part and sorbitan polyethylene glycol ether groups as the hydrophilic part.

Ⅱ. Quality Standards

(Polysorbate-80 will abide by the Standard CP2015, and other series will abide by the Standard USP32).

III.Applications

In the pharmaceutical industry, the products of Span series are widely used in processing of finished drugs in various dosage forms, used for solubilizer and emulsifier of injection and oral liquid, disintegrating agents of tablets, dispersant of capsules, emulsifier and matrix of ointment, matrix of suppository, etc. In addition, the products of Span, Tween series are the most common emulsifier in the food industry.

IV.Packaging, Storage And Transportation

The products with weights of 25kg kraft bag or200kg iron drum packing, and they should be stored in a cool ventilated place and the preserve temperature should be kept below 40 ℃, meanwhile, insolate, high temperature and humidity are strictly prohibited.  In order to prevent breakage, violent collision should be avoided, and the guarantee period for storage is two years.
The original process of Span-80 was vacuum esterification. The water generated in the reaction was continuously pumped out to facilitate the reaction equilibrium in the direction. The viscosity of the product is less than 40 mg, which is difficult to control due to its high temperature difference.

Span Series
Item Sorbitan fatty acid ester20 Sorbitan fatty acid ester40 Sorbitan fatty acid ester60 Sorbitan fatty acid ester80
HLB value 8.6 6.7 4.7 4.3
Melting Point℃ 25℃ 45-47 52-54 25℃液态
Acid number (mgkOH/g) ≤8 ≤8 ≤10 ≤8
Hydroxyl value(mgkOH/g) 330-358 270-305 235-260 193-210
Saponification value (mgkOH/g) 158-170 140-150 147-157 145-160
Iodine value (mg12/g) —- —– —- 62-76
Heavy metals(ppm)≤ 10 10 10 10
Water % ≤1.5 ≤1.5 ≤1.5 ≤1.5

Residue on Ignition %

≤0.5 ≤0.5 ≤0.5 ≤0.5

  • Previous:
  • Next:

  • Write your message here and send it to us